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Solid-phase synthesis and chemical properties of 2-(2-amino/hydroxyethyl)-1-aryl-3, 4-dihydropyrazino[1, 2-b] indazol-2-iums

Amino alcohols, diamines, benzenesulfonyl chlorides and bromoketones were used to prepare polymer-supported 2-(2-(2-(amino/hydroxyl)ethylamino)ethyl)-3-benzoyl-2H-indazoles. Acid-mediated release yielded 2-((amino/hydroxyl)ethyl)-1-aryl-3,4-dihydropyrazino[1,2-b]indazole-2-iums. In neutral pH, imini...

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Bibliografiske detaljer
Main Authors: Kočí, Jan, Krchňák, Viktor
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811378/
https://ncbi.nlm.nih.gov/pubmed/19961214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cc9001422
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