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Zn(2+) regulates Kv2.1 voltage-dependent gating and localization following ischemia
The delayed-rectifier K(+) channel Kv2.1 exists in highly phosphorylated somatodendritic clusters. Ischemia induces rapid Kv2.1 dephosphorylation and a dispersal of these clusters, accompanied by a hyperpolarizing shift in their voltage-dependent activation kinetics. Transient modulation of Kv2.1 ac...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2811322/ https://ncbi.nlm.nih.gov/pubmed/20092568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2009.07026.x |
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