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De novo recruitment of antigen-experienced and naïve T cells contributes to the long term maintenance of anti-viral T cell populations in the persistently infected CNS

Mice infected with attenuated strains of mouse hepatitis virus, strain JHM develop a chronic infection in the brain and spinal cord characterized by low levels of viral antigen persistence and retention of virus-specific CD4 and CD8 T cells at the site of infection. It is not known whether these cel...

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Dettagli Bibliografici
Autori principali: Zhao, Jingxian, Zhao, Jincun, Perlman, Stanley
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811315/
https://ncbi.nlm.nih.gov/pubmed/19786545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902164
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