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Bacterial flagellin stimulates TLR5-dependent defense against vancomycin-resistant Enterococcus infection

Treatment of vancomycin-resistant Enterococcus (VRE) infections is limited by the paucity of effective antibiotics. Administration of broad-spectrum antibiotics promotes VRE colonization by down-regulating homeostatic innate immune defenses. Intestinal epithelial cells and Paneth cells express antim...

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Detalhes bibliográficos
Main Authors: Kinnebrew, Melissa A., Ubeda, Carles, Zenewicz, Lauren A., Smith, Nichole, Flavell, Richard A., Pamer, Eric G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811237/
https://ncbi.nlm.nih.gov/pubmed/20064069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/650203
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