TLR-7 activation enhances IL-22–mediated colonization resistance against vancomycin-resistant enterococcus

Antibiotic administration can disrupt the intestinal microbiota and down-regulate innate immune defenses, compromising colonization resistance against orally acquired bacterial pathogens. Vancomycin-resistant Enterococcus faecium (VRE), a major cause of antibiotic-resistant infections in hospitalize...

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Publicat a:Sci Transl Med
Autors principals: Abt, Michael C., Buffie, Charlie G., Sušac, Bože, Becattini, Simone, Carter, Rebecca A., Leiner, Ingrid, Keith, James W., Artis, David, Osborne, Lisa C., Pamer, Eric G.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991618/
https://ncbi.nlm.nih.gov/pubmed/26912904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aad6663
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