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Roles of the Src Tyrosine Kinases Lck and Fyn in Regulating γδTCR Signal Strength
Lck and Fyn, members of the Src family of tyrosine kinases, are key components of the αβTCR-coupled signaling pathway. While it is generally accepted that both Lck and Fyn positively regulate signal transduction by the αβTCR, recent studies have shown that Lck and Fyn have distinct functions in this...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2811189/ https://ncbi.nlm.nih.gov/pubmed/20126650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008899 |
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