Rare Variants Create Synthetic Genome-Wide Associations

Genome-wide association studies (GWAS) have now identified at least 2,000 common variants that appear associated with common diseases or related traits (http://www.genome.gov/gwastudies), hundreds of which have been convincingly replicated. It is generally thought that the associated markers reflect...

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Bibliographic Details
Main Authors: Dickson, Samuel P., Wang, Kai, Krantz, Ian, Hakonarson, Hakon, Goldstein, David B.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811148/
https://ncbi.nlm.nih.gov/pubmed/20126254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000294
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