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Phospholipase Cβ4 is specifically involved in climbing fiber synapse elimination in the developing cerebellum

Elimination of excess climbing fiber (CF)–Purkinje cell synapses during cerebellar development involves a signaling pathway that includes type 1 metabotropic glutamate receptor, Gαq, and the γ isoform of protein kinase C. To identify phospholipase C (PLC) isoforms involved in this process, we genera...

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I publikationen:Proc Natl Acad Sci U S A
Huvudupphov: Kano, Masanobu, Hashimoto, Kouichi, Watanabe, Masahiko, Kurihara, Hideo, Offermanns, Stefan, Jiang, Huiping, Wu, Yanping, Jun, Kisun, Shin, Hee-Sup, Inoue, Yoshiro, Simon, Melvin I., Wu, Dianqing
Materialtyp: Artigo
Språk:Inglês
Utgiven: National Academy of Sciences 1998
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC28111/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9861037/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.26.15724
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