Maturation of Cerebellar Purkinje Cell Population Activity during Postnatal Refinement of Climbing Fiber Network

Neural circuits undergo massive refinements during postnatal development. In the developing cerebellum, the climbing fiber (CF) to Purkinje cell (PC) network is drastically reshaped by eliminating early-formed redundant CF to PC synapses. To investigate the impact of CF network refinement on PC popu...

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Auteurs principaux:	Jean-Marc Good, Michael Mahoney, Taisuke Miyazaki, Kenji F. Tanaka, Kenji Sakimura, Masahiko Watanabe, Kazuo Kitamura, Masanobu Kano
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2017-11-01
Collection:	Cell Reports
Sujets:	cerebellum Purkinje cell climbing fiber postnatal development in vivo calcium imaging 2-photon microscopy population activity synapse elimination
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S2211124717315814
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