Effects of the AT(1) Receptor Antagonist L-158,809 on Microglia and Neurogenesis after Fractionated Whole-Brain Irradiation

Cognitive dysfunction develops in approximately 50% of patients who receive fractionated whole-brain irradiation and survive 6 months or more. The mechanisms underlying these deficits are unknown. A recent study demonstrated that treatment with the angiotensin II type 1 receptor antagonist (AT(1)RA)...

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Main Authors: Conner, Kelly R., Payne, Valerie S., Forbes, M. Elizabeth, Robbins, Mike E., Riddle, David R.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811039/
https://ncbi.nlm.nih.gov/pubmed/20041759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR1821.1
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