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The tumor suppressor, parafibromin, mediates histone H3 K9 methylation for cyclin D1 repression
Parafibromin, a component of the RNA polymerase II-associated PAF1 complex, is a tumor suppressor linked to hyperparathyroidism-jaw tumor syndrome and sporadic parathyroid carcinoma. Parafibromin induces cell cycle arrest by repressing cyclin D1 via an unknown mechanism. Here, we show that parafibro...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2811029/ https://ncbi.nlm.nih.gov/pubmed/19906718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp991 |
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