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Probing the (H3-H4)(2) histone tetramer structure using pulsed EPR spectroscopy combined with site-directed spin labelling

The (H3-H4)(2) histone tetramer forms the central core of nucleosomes and, as such, plays a prominent role in assembly, disassembly and positioning of nucleosomes. Despite its fundamental role in chromatin, the tetramer has received little structural investigation. Here, through the use of pulsed el...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bowman, Andrew, Ward, Richard, El-Mkami, Hassane, Owen-Hughes, Tom, Norman, David G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810997/
https://ncbi.nlm.nih.gov/pubmed/19914933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1003
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