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Probing the (H3-H4)(2) histone tetramer structure using pulsed EPR spectroscopy combined with site-directed spin labelling

The (H3-H4)(2) histone tetramer forms the central core of nucleosomes and, as such, plays a prominent role in assembly, disassembly and positioning of nucleosomes. Despite its fundamental role in chromatin, the tetramer has received little structural investigation. Here, through the use of pulsed el...

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Autors principals: Bowman, Andrew, Ward, Richard, El-Mkami, Hassane, Owen-Hughes, Tom, Norman, David G.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810997/
https://ncbi.nlm.nih.gov/pubmed/19914933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1003
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