Загрузка...
Induction of immune tolerance to FIX by intramuscular AAV gene transfer is independent of the activation status of dendritic cells
The nature of viral vectors is suggested to be a significant contributor to undesirable immune responses subsequent to gene transfer. Such viral vectors, recognized as danger signals by the host immune system, activate dendritic cells (DCs), causing unwanted antivector and/or transgene product immun...
Сохранить в:
| Главные авторы: | , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society of Hematology
2010
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2810988/ https://ncbi.nlm.nih.gov/pubmed/19965663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-239509 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|