Foxp1 is an essential transcriptional regulator for the generation of quiescent naive T cells during thymocyte development

Proper thymocyte development is required to establish T-cell central tolerance and to generate naive T cells, both of which are essential for T-cell homeostasis and a functional immune system. Here we demonstrate that the loss of transcription factor Foxp1 results in the abnormal development of T ce...

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Detalhes bibliográficos
Main Authors: Feng, Xiaoming, Ippolito, Gregory C., Tian, Lifeng, Wiehagen, Karla, Oh, Soyoung, Sambandam, Arivazhagan, Willen, Jessica, Bunte, Ralph M., Maika, Shanna D., Harriss, June V., Caton, Andrew J., Bhandoola, Avinash, Tucker, Philip W., Hu, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810984/
https://ncbi.nlm.nih.gov/pubmed/19965654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-232694
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