A partial cDNA clone of trypomastigote decay-accelerating factor (T-DAF), a developmentally regulated complement inhibitor of Trypanosoma cruzi, has genetic and functional similarities to the human complement inhibitor DAF.

Resistance to complement-mediated lysis in Trypanosoma cruzi is due to the expression of complement-regulatory factors by the virulent developmental forms of this protozoan parasite. An 87- to 93-kDa molecule, which we have termed T-DAF (trypomastigote decay-accelerating factor), is present on the s...

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Dettagli Bibliografici
Autori principali: Tambourgi, D V, Kipnis, T L, da Silva, W D, Joiner, K A, Sher, A, Heath, S, Hall, B F, Ogden, G B
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1993
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC281061/
https://ncbi.nlm.nih.gov/pubmed/7689538
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