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Adaptation of Venezuelan equine encephalitis virus lacking 51-nt conserved sequence element to replication in mammalian and mosquito cells

Replication of alphaviruses strongly depends on the promoters located in the plus- and minus-strands of virus-specific RNAs. The most sophisticated promoter is encoded by the 5′ end of the viral genome. This RNA sequence is involved in initiation of translation of viral nsPs, and synthesis of both m...

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Autori principali: Michel, Gilles, Petrakova, Olga, Atasheva, Svetlana, Frolov, Ilya
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810489/
https://ncbi.nlm.nih.gov/pubmed/17292936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.01.009
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