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IRES-dependent replication of Venezuelan equine encephalitis virus makes it highly attenuated and incapable of replicating in mosquito cells

The development of infectious cDNA for different alphaviruses opened an opportunity to explore their attenuation by extensively modifying the viral genomes, an approach that might minimize or exclude the reversion to the wild-type, pathogenic phenotype. Moreover, the genomes of such alphaviruses can...

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Bibliografiske detaljer
Main Authors: Volkova, Eugenia, Frolova, Elena, Darwin, Justin, Forrester, Naomi L., Weaver, Scott C., Frolov, Ilya
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483425/
https://ncbi.nlm.nih.gov/pubmed/18501401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.04.020
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