Mutational Analysis of Highly Conserved Residues in the Phage PhiC31 Integrase Reveals Key Amino Acids Necessary for the DNA Recombination

BACKGROUND: Amino acid sequence alignment of phage phiC31 integrase with the serine recombinases family revealed highly conserved regions outside the catalytic domain. Until now, no system mutational or biochemical studies have been carried out to assess the roles of these conserved residues in the...

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Detaylı Bibliyografya
Asıl Yazarlar: Liu, Shaohui, Ma, Jinfang, Wang, Wei, Zhang, Maoxiang, Xin, Qingting, Peng, Siman, Li, Rongxiu, Zhu, Huanzhang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2010
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810336/
https://ncbi.nlm.nih.gov/pubmed/20111606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008863
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