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TLR4 signaling in effector CD4(+) T cells regulates TCR activation and experimental colitis in mice
TLRs sense various microbial products. Their function has been best characterized in DCs and macrophages, where they act as important mediators of innate immunity. TLR4 is also expressed on CD4(+) T cells, but its physiological function on these cells remains unknown. Here, we have shown that TLR4 t...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2810084/ https://ncbi.nlm.nih.gov/pubmed/20051628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40055 |
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