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Toll-like receptor 9–induced type I IFN protects mice from experimental colitis

Experimental colitis is mediated by inflammatory or dysregulated immune responses to microbial factors of the gastrointestinal tract. In this study we observed that administration of Toll-like receptor 9 (TLR9) agonists suppressed the severity of experimental colitis in RAG1(–/–) but not in SCID mic...

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Bibliografiske detaljer
Main Authors: Katakura, Kyoko, Lee, Jongdae, Rachmilewitz, Daniel, Li, Gloria, Eckmann, Lars, Raz, Eyal
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1051992/
https://ncbi.nlm.nih.gov/pubmed/15765149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200522996
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