Polyenephosphatidylcholine prevents alcoholic liver disease in PPARα-null mice through attenuation of increases in oxidative stress

BACKGROUND/AIMS: Alcoholic liver disease (ALD) is one of the leading causes of cirrhosis and yet efficient therapeutic strategies are lacking. Polyenephospha tidylcholine (PPC), a major component of essential phospholipids, prevented alcoholic liver fibrosis in baboons, but its precise mechanism rem...

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Bibliographic Details
Main Authors: Okiyama, Wataru, Tanaka, Naoki, Nakajima, Tamie, Tanaka, Eiji, Kiyosawa, Kendo, Gonzalez, Frank J., Aoyama, Toshifumi
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809859/
https://ncbi.nlm.nih.gov/pubmed/19398233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2009.01.025
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