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Reactive Oxygen Species Mediate Mitogenic Growth Factor Signaling Pathways in Human Leiomyoma Smooth Muscle Cells

Uterine leiomyomas are benign uterine tumors characterized by extracellular matrix remodeling, increased collagen deposition, and increased smooth muscle cell (SMC) proliferation. The reactive oxygen species (ROS) producing NADPH oxidase complex has been shown to be involved in the signaling pathway...

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Detalhes bibliográficos
Main Authors: Mesquita, Fernando S., Dyer, Summer N., Heinrich, Daniel A., Bulun, Serdar E., Marsh, Erica E., Nowak, Romana A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809225/
https://ncbi.nlm.nih.gov/pubmed/19741209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.108.075887
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