Plasma phosphorylated-TDP-43 protein levels correlate with brain pathology in frontotemporal lobar degeneration

In the present study, we have correlated plasma TDP-43 levels, as measured by ELISA, with the presence of TDP-43 pathological changes in the brains of 28 patients with frontotemporal lobar degeneration (FTLD) (14 with FTLD-TDP and 14 with FTLD-tau) and 24 patients with pathologically confirmed AD (8...

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Main Authors: Foulds, Penelope G., Davidson, Yvonne, Mishra, Manjari, Hobson, David J., Humphreys, Kirsty M., Taylor, Mark, Johnson, Nancy, Weintraub, Sandra, Akiyama, Haruhiko, Arai, Tetsuaki, Hasegawa, Masato, Bigio, Eileen H., Benson, Fiona E., Allsop, David, Mann, David M. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809136/
https://ncbi.nlm.nih.gov/pubmed/19823856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-009-0594-0
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