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Intact Cytoskeleton Is Required for Small G Protein Dependent Activation of the Epithelial Na(+) Channel

BACKGROUND: The Epithelial Na(+) Channel (ENaC) plays a central role in control of epithelial surface hydration and vascular volume. Similar to other ion channels, ENaC activity is regulated, in part, by cortical cytoskeleton. Besides, the cytoskeleton is an established target for small G proteins s...

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Detalhes bibliográficos
Main Authors: Karpushev, Alexey V., Ilatovskaya, Daria V., Pavlov, Tengis S., Negulyaev, Yuri A., Staruschenko, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809106/
https://ncbi.nlm.nih.gov/pubmed/20098689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008827
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