Correlation between expression of p53, p21/WAF1, and MDM2 proteins and their prognostic significance in primary hepatocellular carcinoma

BACKGROUND: Tumor Protein p53 (p53), cyclin-dependent kinase inhibitor 1A (p21/WAF1), and murine double minute 2 (MDM2) participate in the regulation of cell growth. Altered expression of these gene products has been found in malignant tumors and has been associated with poor prognosis. Our aim was...

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Bibliografiske detaljer
Main Authors: Zhang, Mei-Fang, Zhang, Zhi-Yi, Fu, Jia, Yang, Yu-Feng, Yun, Jing-Ping
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809055/
https://ncbi.nlm.nih.gov/pubmed/20025780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-7-110
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