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Proteus mirabilis urease: histidine 320 of UreC is essential for urea hydrolysis and nickel ion binding within the native enzyme.

Proteus mirabilis urease, a nickel-containing enzyme, has been established as a critical virulence determinant in urinary tract infection. An amino acid sequence (residues 308 to 327: TVDEHLDMLMVCHHLDPSIP) within the large urease subunit, UreC, is highly conserved for every urease examined thus far...

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Podrobná bibliografie
Vydáno v:Infect Immun
Hlavní autoři: Sriwanthana, B, Mobley, H L
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1993
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280886/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8500894/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.61.6.2570-2577.1993
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