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Expression of catalytically active recombinant Helicobacter pylori urease at wild-type levels in Escherichia coli.

The genes encoding Helicobacter pylori urease, a nickel metalloenzyme, have been cloned and expressed in Escherichia coli. Enzymatic activity, however, has been very weak compared with that in clinical isolates of H. pylori. Conditions under which near wild-type urease activity was achieved were dev...

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Bibliografische gegevens
Gepubliceerd in:Infect Immun
Hoofdauteurs: Hu, L T, Mobley, H L
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 1993
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280885/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8500893/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.61.6.2563-2569.1993
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