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Tackling the methylome: recent methodological advances in genome-wide methylation profiling

DNA methylation of promoter CpG islands is strongly associated with gene silencing and is known as a frequent cause of loss of expression of tumor suppressor genes, as well as other genes involved in tumor formation. DNA methylation of driver genes is very likely outnumbered by the number of methyla...

詳細記述

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書誌詳細
主要な著者: Estécio, Marcos RH, Issa, Jean-Pierre J
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808741/
https://ncbi.nlm.nih.gov/pubmed/19930617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm106
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