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Functional consequences of the human leptin receptor (LEPR) Q223R transversion
Perturbations in the functional integrity of the leptin axis are obvious candidates for mediation of altered adiposity. In a large number of genetic association studies in humans, the non-conservative LEPR Q223R allele has been inconsistently associated with adiposity. Subtle, long term effects of s...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2808713/ https://ncbi.nlm.nih.gov/pubmed/18997673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oby.2008.489 |
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