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In vitro evaluation of pan-PI3-kinase inhibitor SF1126 in trastuzumab-sensitive and trastuzumab-resistant HER2-over-expressing breast cancer cells
PURPOSE: The purpose of the current study is to determine the in vitro cytotoxic effects of the novel pan-PI3-kinase inhibitor SF1126 in HER2-over-expressing breast cancer cells. METHODS: Cell proliferation and cytotoxicity were examined by MTS colorimetric assay, FACS analysis, colony formation ass...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer-Verlag
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2808522/ https://ncbi.nlm.nih.gov/pubmed/19636556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-009-1075-9 |
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