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Nordihydroguaiaretic Acid, a Cytotoxic IGF-IR/HER2 Inhibitor in Trastuzumab-Resistant Breast Cancer

The majority of patients with HER2-overexpressing metastatic breast cancer who initially respond to the HER2-targeted antibody trastuzumab demonstrate disease progression within one year. The identification of novel agents that effectively inhibit survival of cancer cells that have progressed on tra...

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Autori principali: Rowe, Danica L., Ozbay, Tuba, Bender, Laura M., Nahta, Rita
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586607/
https://ncbi.nlm.nih.gov/pubmed/18645000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0012
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