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A Modeling Study of T-Type Ca(2+) Channel Gating and Modulation by L-Cysteine in Rat Nociceptors
L-cysteine (L-cys) increases the amplitude of T-type Ca(2+) currents in rat T-rich nociceptor-like dorsal root ganglia neurons. The modulation of T-type Ca(2+) channel gating by L-cys was studied by fitting Markov state models to whole-cell currents recorded from T-rich neurons. The best fitting mod...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Biophysical Society
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2808491/ https://ncbi.nlm.nih.gov/pubmed/20338841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.10.007 |
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