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Inhibition of TLR4 signaling prolongs Treg-dependent murine islet allograft survival
Toll-like receptors (TLRs) provide an important link between innate and adaptive immune system. We hypothesized that the recognition of endogenous TLR4 ligands is occurring at the time of transplantation, and these innate signals drive the inflammation and affect alloimmune responses. We confirmed t...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2808455/ https://ncbi.nlm.nih.gov/pubmed/19879295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2009.10.004 |
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