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A Role for Non-Covalent SUMO Interaction Motifs in Pc2/CBX4 E3 Activity

BACKGROUND: Modification of proteins by the small ubiquitin like modifier (SUMO) is an essential process in mammalian cells. SUMO is covalently attached to lysines in target proteins via an enzymatic cascade which consists of E1 and E2, SUMO activating and conjugating enzymes. There is also a variab...

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Bibliografiska uppgifter
Huvudupphovsmän: Merrill, Jacqueline C., Melhuish, Tiffany A., Kagey, Michael H., Yang, Shen-Hsi, Sharrocks, Andrew D., Wotton, David
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808386/
https://ncbi.nlm.nih.gov/pubmed/20098713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008794
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