A Role for Non-Covalent SUMO Interaction Motifs in Pc2/CBX4 E3 Activity

BACKGROUND: Modification of proteins by the small ubiquitin like modifier (SUMO) is an essential process in mammalian cells. SUMO is covalently attached to lysines in target proteins via an enzymatic cascade which consists of E1 and E2, SUMO activating and conjugating enzymes. There is also a variab...

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Bibliografiske detaljer
Main Authors: Merrill, Jacqueline C., Melhuish, Tiffany A., Kagey, Michael H., Yang, Shen-Hsi, Sharrocks, Andrew D., Wotton, David
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808386/
https://ncbi.nlm.nih.gov/pubmed/20098713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008794
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