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An extended consensus motif enhances the specificity of substrate modification by SUMO

Protein modification by SUMO conjugation is an important regulatory event. Sumoylation usually takes place on a lysine residue embedded in the core consensus motif ψKxE. However, this motif confers limited specificity on the sumoylation process. Here, we have probed the roles of clusters of acidic r...

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Autori principali: Yang, Shen-Hsi, Galanis, Alex, Witty, James, Sharrocks, Andrew D
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1630412/
https://ncbi.nlm.nih.gov/pubmed/17036045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601383
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