Improving the efficiency of genomic loci capture using oligonucleotide arrays for high throughput resequencing

BACKGROUND: The emergence of next-generation sequencing technology presents tremendous opportunities to accelerate the discovery of rare variants or mutations that underlie human genetic disorders. Although the complete sequencing of the affected individuals' genomes would be the most powerful...

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Bibliografiske detaljer
Main Authors: Lee, Hane, O'Connor, Brian D, Merriman, Barry, Funari, Vincent A, Homer, Nils, Chen, Zugen, Cohn, Daniel H, Nelson, Stanley F
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Methodology article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808330/
https://ncbi.nlm.nih.gov/pubmed/20043857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-646
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