Improving the efficiency of genomic loci capture using oligonucleotide arrays for high throughput resequencing

BACKGROUND: The emergence of next-generation sequencing technology presents tremendous opportunities to accelerate the discovery of rare variants or mutations that underlie human genetic disorders. Although the complete sequencing of the affected individuals' genomes would be the most powerful...

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Bibliographische Detailangaben
Hauptverfasser: Lee, Hane, O'Connor, Brian D, Merriman, Barry, Funari, Vincent A, Homer, Nils, Chen, Zugen, Cohn, Daniel H, Nelson, Stanley F
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
Schlagworte:
Methodology article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808330/
https://ncbi.nlm.nih.gov/pubmed/20043857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-646
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