Improving the efficiency of genomic loci capture using oligonucleotide arrays for high throughput resequencing

BACKGROUND: The emergence of next-generation sequencing technology presents tremendous opportunities to accelerate the discovery of rare variants or mutations that underlie human genetic disorders. Although the complete sequencing of the affected individuals' genomes would be the most powerful...

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Detalhes bibliográficos
Main Authors: Lee, Hane, O'Connor, Brian D, Merriman, Barry, Funari, Vincent A, Homer, Nils, Chen, Zugen, Cohn, Daniel H, Nelson, Stanley F
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Methodology article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808330/
https://ncbi.nlm.nih.gov/pubmed/20043857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-646
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