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The posteriorizing gene Gbx2 is a direct target of Wnt signalling and the earliest factor in neural crest induction
Wnt signalling is required for neural crest (NC) induction; however, the direct targets of the Wnt pathway during NC induction remain unknown. We show here that the homeobox gene Gbx2 is essential in this process and is directly activated by Wnt/β-catenin signalling. By ChIP and transgenesis analysi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2808295/ https://ncbi.nlm.nih.gov/pubmed/19736322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.036954 |
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