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The posteriorizing gene Gbx2 is a direct target of Wnt signalling and the earliest factor in neural crest induction

Wnt signalling is required for neural crest (NC) induction; however, the direct targets of the Wnt pathway during NC induction remain unknown. We show here that the homeobox gene Gbx2 is essential in this process and is directly activated by Wnt/β-catenin signalling. By ChIP and transgenesis analysi...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Li, Bo, Kuriyama, Sei, Moreno, Mauricio, Mayor, Roberto
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Company of Biologists 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808295/
https://ncbi.nlm.nih.gov/pubmed/19736322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.036954
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