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Opiate-Induced Suppression of Rat Hypoglossal Motoneuron Activity and Its Reversal by Ampakine Therapy

BACKGROUND: Hypoglossal (XII) motoneurons innervate tongue muscles and are vital for maintaining upper-airway patency during inspiration. Depression of XII nerve activity by opioid analgesics is a significant clinical problem, but underlying mechanisms are poorly understood. Currently there are no s...

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Detalhes bibliográficos
Main Authors: Lorier, Amanda R., Funk, Gregory D., Greer, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808240/
https://ncbi.nlm.nih.gov/pubmed/20098731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008766
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