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Regularized estimation of large-scale gene association networks using graphical Gaussian models

BACKGROUND: Graphical Gaussian models are popular tools for the estimation of (undirected) gene association networks from microarray data. A key issue when the number of variables greatly exceeds the number of samples is the estimation of the matrix of partial correlations. Since the (Moore-Penrose)...

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Detalhes bibliográficos
Main Authors: Krämer, Nicole, Schäfer, Juliane, Boulesteix, Anne-Laure
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808166/
https://ncbi.nlm.nih.gov/pubmed/19930695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-384
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