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Platelet-Derived Growth Factor-B Normalizes Micromorphology and Vessel Function in Vascular Endothelial Growth Factor-A-Induced Squamous Cell Carcinomas

Vascular endothelial growth factor (VEGF), which is a key regulator of angiogenesis, often induces formation of immature vessels with increased permeability and reduced vessel functionality. Here, we demonstrate that de novo expression of murine (m)VEGF-164 induces malignant and invasive tumor growt...

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Bibliographic Details
Main Authors: Lederle, Wiltrud, Linde, Nina, Heusel, Julia, Bzyl, Jessica, Woenne, Eva C., Zwick, Stefan, Skobe, Mihaela, Kiessling, Fabian, Fusenig, Norbert E., Mueller, Margareta M.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808101/
https://ncbi.nlm.nih.gov/pubmed/20042679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.080998
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