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Tumorigenic conversion of immortal human keratinocytes through stromal cell activation

The stromal microenvironment plays a crucial role in tumor development and progression. One of the most potent activators of stromal cells is the platelet-derived growth factor (PDGF). To investigate the role of PDGF in epithelial tumor development we stably transfected immortal nontumorigenic human...

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Hlavní autoři: Skobe, Mihaela, Fusenig, Norbert E.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC18668/
https://ncbi.nlm.nih.gov/pubmed/9448283
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