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Tumorigenic conversion of immortal human keratinocytes through stromal cell activation

The stromal microenvironment plays a crucial role in tumor development and progression. One of the most potent activators of stromal cells is the platelet-derived growth factor (PDGF). To investigate the role of PDGF in epithelial tumor development we stably transfected immortal nontumorigenic human...

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Detalhes bibliográficos
Main Authors: Skobe, Mihaela, Fusenig, Norbert E.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC18668/
https://ncbi.nlm.nih.gov/pubmed/9448283
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