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An Innate Path to Human B Cell Tolerance

Self-reactive B cells are eliminated during development by antibody-affinity selection and receptor-editing mechanisms. Work by Isnardi et al. (2008) in this issue of Immunity suggests that removal of autoreactivity from the immature B cell pool also requires innate immunity pathways.

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Hlavní autor: Bolland, Silvia
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807984/
https://ncbi.nlm.nih.gov/pubmed/19006689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.10.001
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