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An Innate Path to Human B Cell Tolerance
Self-reactive B cells are eliminated during development by antibody-affinity selection and receptor-editing mechanisms. Work by Isnardi et al. (2008) in this issue of Immunity suggests that removal of autoreactivity from the immature B cell pool also requires innate immunity pathways.
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2807984/ https://ncbi.nlm.nih.gov/pubmed/19006689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.10.001 |
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