Disulfide-Dependent Self-Assembly of Adiponectin Octadecamers from Trimers and Presence of Stable Octadecameric Adiponectin Lacking Disulfide Bonds In Vitro

Adiponectin is a circulating insulin-sensitizing hormone that homo-oligomerizes into trimers, hexamers, and higher molecular weight (HMW) species. Low levels of circulating HMW adiponectin appear to increase the risk for insulin resistance. Currently, assembly of adiponectin oligomers, and consequen...

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Detalhes bibliográficos
Main Authors: Briggs, David B., Jones, Christopher M., Mashalidis, Ellene H., Nuñez, Martha, Hausrath, Andrew C., Wysocki, Vicki H., Tsao, Tsu-Shuen
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807922/
https://ncbi.nlm.nih.gov/pubmed/19943704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9015555
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