Disulfide-Dependent Self-Assembly of Adiponectin Octadecamers from Trimers and Presence of Stable Octadecameric Adiponectin Lacking Disulfide Bonds In Vitro

Adiponectin is a circulating insulin-sensitizing hormone that homo-oligomerizes into trimers, hexamers, and higher molecular weight (HMW) species. Low levels of circulating HMW adiponectin appear to increase the risk for insulin resistance. Currently, assembly of adiponectin oligomers, and consequen...

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Autori principali: Briggs, David B., Jones, Christopher M., Mashalidis, Ellene H., Nuñez, Martha, Hausrath, Andrew C., Wysocki, Vicki H., Tsao, Tsu-Shuen
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807922/
https://ncbi.nlm.nih.gov/pubmed/19943704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9015555
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