In vitro amplification of prions from milk in the detection of subclinical infections

Prions can be amplified by serial protein misfolding cyclic amplification (sPMCA) from the milk of a high proportion of apparently healthy, scrapie exposed sheep with PRNP genotypes not previously associated with high disease penetrance.1 These data strongly suggest the widespread presence of subcli...

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Hlavní autoři: Gough, Kevin C, Baker, Claire A, Taema, Maged, Maddison, Ben C
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807697/
https://ncbi.nlm.nih.gov/pubmed/19949303
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