The chemokine receptor antagonist, TAK-779, decreased experimental autoimmune encephalomyelitis by reducing inflammatory cell migration into the central nervous system, without affecting T cell function

BACKGROUND AND PURPOSE: The C–C chemokine receptor CCR5, and the C–X–C chemokine receptor CXCR3 are involved in the regulation of T cell-mediated immune responses, and in the migration and activation of these cells. To determine whether blockade of these chemokine receptors modulated inflammatory re...

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Detalhes bibliográficos
Main Authors: Ni, Jia, Zhu, Yi-Na, Zhong, Xiang-Gen, Ding, Yu, Hou, Li-Fei, Tong, Xian-Kun, Tang, Wei, Ono, Shiro, Yang, Yi-Fu, Zuo, Jian-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807666/
https://ncbi.nlm.nih.gov/pubmed/20050195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00528.x
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