TRPM2 Exacerbates Central Nervous System Inflammation in Experimental Autoimmune Encephalomyelitis by Increasing Production of CXCL2 Chemokines

Multiple sclerosis (MS) is a chronic inflammatory disorder of the CNS characterized by demyelination and axonal injury. Current therapies that mainly target lymphocytes do not fully meet clinical need due to the risk of severe side effects and lack of efficacy against progressive MS. Evidence sugges...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Tsutsui, Masato, Hirase, Ryo, Miyamura, Sakie, Nagayasu, Kazuki, Nakagawa, Takayuki, Mori, Yasuo, Shirakawa, Hisashi, Kaneko, Shuji
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596171/
https://ncbi.nlm.nih.gov/pubmed/30201769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2203-17.2018
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