TRPM2 Exacerbates Central Nervous System Inflammation in Experimental Autoimmune Encephalomyelitis by Increasing Production of CXCL2 Chemokines

Multiple sclerosis (MS) is a chronic inflammatory disorder of the CNS characterized by demyelination and axonal injury. Current therapies that mainly target lymphocytes do not fully meet clinical need due to the risk of severe side effects and lack of efficacy against progressive MS. Evidence sugges...

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Publicat a:J Neurosci
Autors principals: Tsutsui, Masato, Hirase, Ryo, Miyamura, Sakie, Nagayasu, Kazuki, Nakagawa, Takayuki, Mori, Yasuo, Shirakawa, Hisashi, Kaneko, Shuji
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2018
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596171/
https://ncbi.nlm.nih.gov/pubmed/30201769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2203-17.2018
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